Antiparkinson drugs are medications used to treat the symptoms of Parkinson’s disease.
Most of these agents act by either increasing dopamine activity or reducing acetylcholine activity in the central nervous system. This pharmacology lecture covers topics such as pathophysiology of Parkinson’s disease, striatum and substantia nigra, role of dopamine, GABA, and acetylcholine, MAO-B and COMT metabolism, mechanism of action and side effects of antiparkinson drugs. Drugs mentioned include; Levodopa, Carbidopa, Entacapone, Selegiline, Rasagiline, Bromocriptine, Ropinirole, Pramipexole, Rotigotine, Apomorphine, Benztropine, Biperiden, Procyclidine, Trihexyphenidyl, and Amantadine.
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